Manufacturer: Country Life Animal Health Registered Name Musca-Ban Insecticidal Spray Composition Each L contains pyrethrins 1.5 g, di-N-propyl isocinchomeronate 6 g, piperonyl butoxide 2.7 g, N-octyl bicycloheptene dicarboximide 3 g, citronella oil 5 g. Actions Insecticide; insect repellent. Pharmacology. Pyrethrins are organic esters which are the active insecticidal constituents of the Chrysanthemum cinerariaefolium flower. They exert potent insecticidal and insect repellent actions and have a broad spectrum of activity. Pyrethrins are rapidly neurotoxic to several insect species including Stomoxys calcitrans, Musca domestica and Lucilia cuprina, all of which commonly infest wound sites. In contrast to their toxicity to insects, pyrethrins possess extremely low mammalian toxicity due to their lability in the gastrointestinal tract and rapid metabolism in the liver. They do not accumulate in mammalian tissue and are nonirritant to mammalian skin. Piperonyl butoxide is a pyrethrin synergist which inhibits the breakdown of pyrethrins by insect enzyme systems, thus prolonging the action of pyrethrins. N-octyl bicycloheptene dicarboximide (MGK 264) is an insecticide synergist which enhances the action of pyrethrins. It acts by inhibiting microsomal oxidation and preventing the insect from denaturing the pyrethrins. MGK 264, through absorption of ultraviolet light, stabilises pyrethrins which would otherwise be rapidly broken down in sunlight. The toxicity of N-octyl bicycloheptene dicarboximide to mammals is very low. Di-N-propyl isocinchomeronate (MGK 326) is a synthetic insect repellent with extremely low mammalian toxicity. MGK 326 acts to enhance the insect repellent properties of the pyrethrins. Clinical trials have demonstrated that MGK 326 is not present in the milk of cows sprayed with di-N-propyl isocinchomeronate. Citronella oil is an insect repellent obtained by distillation from members of the Gramineae family. Citronella oil has been shown to enhance the residual toxicity of pyrethrins to specific insect groups. Indications Flies and mosquitoes on horses, dogs, cattle and pigs; fleas and lice on dogs and cats. Precautions Avoid direct application to eyes, nose and mouth. May cause dribbling and unsteady gait in cats. If one or both occur, wipe off excess product and contact a veterinarian. First aid. If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131 126. Withholding Periods Nil. Directions for use Apply sparingly to the hair coat using the spray nozzle or a cloth dampened with Musca-Ban once daily, or twice daily in severe infestation. Spray areas where fleas are likely to breed such as kennels and bedding.